Proteomics and cancer: running before we can walk?

E Check - Nature, 2004 - go.gale.com
E Check
Nature, 2004go.gale.com
[illus. 1] Seldom does a single piece of research prompt the US Congress to pass a
resolution urging continued funding to drive a new diagnostic test towards the clinic. But
that's what happened in 2002, when< pres: italics> The Lancet</pres: italics> published a
paper [1] claiming a breakthrough in the diagnosis of ovarian cancer.The paper described
the use of mass spectrometry to analyse the pattern of proteins present in samples of blood
serum. On the basis of these patterns, the test detected all the patients with ovarian cancers …
[illus. 1] Seldom does a single piece of research prompt the US Congress to pass a resolution urging continued funding to drive a new diagnostic test towards the clinic. But that's what happened in 2002, when< pres: italics> The Lancet published a paper [1] claiming a breakthrough in the diagnosis of ovarian cancer.
The paper described the use of mass spectrometry to analyse the pattern of proteins present in samples of blood serum. On the basis of these patterns, the test detected all the patients with ovarian cancers in a set of 50 samples, and falsely identified just three healthy patients as suffering from the disease from a total of 66 control samples.
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