[HTML][HTML] In vitro biomarker discovery for atherosclerosis by proteomics
EM Fach, LA Garulacan, J Gao, Q Xiao… - Molecular & Cellular …, 2004 - ASBMB
The purpose of this study was to identify in vitro and then prioritize a tractable set of protein
biomarker candidates of atherosclerosis that may eventually be developed to measure the
extent, progression, regression, and stability of atherosclerotic lesions. A study was
conducted using an in vitro" foam cell" model based on the stimulation of differentiated THP1
cells with oxidized low-density lipoprotein (oxidized LDL) as compared with low-density
lipoprotein (LDL). Analysis of the proteins contained in the cell supernatant using proteome …
biomarker candidates of atherosclerosis that may eventually be developed to measure the
extent, progression, regression, and stability of atherosclerotic lesions. A study was
conducted using an in vitro" foam cell" model based on the stimulation of differentiated THP1
cells with oxidized low-density lipoprotein (oxidized LDL) as compared with low-density
lipoprotein (LDL). Analysis of the proteins contained in the cell supernatant using proteome …
