The inflammatory and immune response to Helicobacter pylori infection
K Robinson, RH Argent, JC Atherton - Best practice & research Clinical …, 2007 - Elsevier
Lifelong Helicobacter pylori infection and its associated gastric inflammation underlie peptic
ulceration and gastric carcinogenesis. The immune and inflammatory responses to H. pylori
are doubly responsible: gastric inflammation is the main mediator of pathology, and the
immune and inflammatory response is ineffective, allowing lifelong bacterial persistence.
However, despite inducing gastric inflammation, most infections do not cause disease, and
bacterial, host and environmental factors determine individual disease risk. Although H …
ulceration and gastric carcinogenesis. The immune and inflammatory responses to H. pylori
are doubly responsible: gastric inflammation is the main mediator of pathology, and the
immune and inflammatory response is ineffective, allowing lifelong bacterial persistence.
However, despite inducing gastric inflammation, most infections do not cause disease, and
bacterial, host and environmental factors determine individual disease risk. Although H …