[HTML][HTML] Mammalian HspB1 (Hsp27) is a molecular sensor linked to the physiology and environment of the cell
AP Arrigo - Cell Stress and Chaperones, 2017 - Elsevier
Constitutively expressed small heat shock protein HspB1 regulates many fundamental
cellular processes and plays major roles in many human pathological diseases. In that
regard, this chaperone has a huge number of apparently unrelated functions that appear
linked to its ability to recognize many client polypeptides that are subsequently modified in
their activity and/or half-life. A major parameter to understand how HspB1 is dedicated to
interact with particular clients in defined cellular conditions relates to its complex …
cellular processes and plays major roles in many human pathological diseases. In that
regard, this chaperone has a huge number of apparently unrelated functions that appear
linked to its ability to recognize many client polypeptides that are subsequently modified in
their activity and/or half-life. A major parameter to understand how HspB1 is dedicated to
interact with particular clients in defined cellular conditions relates to its complex …
