Targeting the mitochondrial unfolded protein response in cancer: opportunities and challenges
JR Inigo, R Kumar, D Chandra - Trends in cancer, 2021 - cell.com
JR Inigo, R Kumar, D Chandra
Trends in cancer, 2021•cell.comIncreasing evidence indicates that a mitochondria-specific stress response referred to as the
'mitochondrial unfolded protein response'(UPR mt) is activated to maintain mitochondrial
integrity and support tumor growth. In this forum article, we discuss the recent advances and
current challenges in therapeutically targeting UPR mt in cancer.
'mitochondrial unfolded protein response'(UPR mt) is activated to maintain mitochondrial
integrity and support tumor growth. In this forum article, we discuss the recent advances and
current challenges in therapeutically targeting UPR mt in cancer.
Increasing evidence indicates that a mitochondria-specific stress response referred to as the ‘mitochondrial unfolded protein response' (UPRmt) is activated to maintain mitochondrial integrity and support tumor growth. In this forum article, we discuss the recent advances and current challenges in therapeutically targeting UPRmt in cancer.
cell.com