[HTML][HTML] ATP consumption promotes cancer metabolism
WJ Israelsen, MG Vander Heiden - Cell, 2010 - cell.com
WJ Israelsen, MG Vander Heiden
Cell, 2010•cell.comCancer cells metabolize glucose by aerobic glycolysis, a phenomenon known as the
Warburg effect. Fang et al.(2010) show that the endoplasmic reticulum enzyme ENTPD5
promotes ATP consumption and favors aerobic glycolysis. The findings suggest that nutrient
uptake in cancer cells is limited by ATP and satisfies energy requirements other than ATP
production.
Warburg effect. Fang et al.(2010) show that the endoplasmic reticulum enzyme ENTPD5
promotes ATP consumption and favors aerobic glycolysis. The findings suggest that nutrient
uptake in cancer cells is limited by ATP and satisfies energy requirements other than ATP
production.
Cancer cells metabolize glucose by aerobic glycolysis, a phenomenon known as the Warburg effect. Fang et al. (2010) show that the endoplasmic reticulum enzyme ENTPD5 promotes ATP consumption and favors aerobic glycolysis. The findings suggest that nutrient uptake in cancer cells is limited by ATP and satisfies energy requirements other than ATP production.
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