The trans Golgi Network: Sorting at the Exit Site of the Golgi Complex
G Griffiths, K Simons - Science, 1986 - science.org
Science, 1986•science.org
The Golgi complex is a series of membrane compartments through which proteins destined
for the plasma membrane, secretory vesicles, and lysosomes move sequentially. A model is
proposed whereby these three different classes of proteins are sorted into different vesicles
in the last Golgi compartment, the trans Golgi network. This compartment corresponds to a
tubular reticulum on the trans side of the Golgi stack, previously called Golgi endoplasmic
reticulum lysosomes (GERL).
for the plasma membrane, secretory vesicles, and lysosomes move sequentially. A model is
proposed whereby these three different classes of proteins are sorted into different vesicles
in the last Golgi compartment, the trans Golgi network. This compartment corresponds to a
tubular reticulum on the trans side of the Golgi stack, previously called Golgi endoplasmic
reticulum lysosomes (GERL).
The Golgi complex is a series of membrane compartments through which proteins destined for the plasma membrane, secretory vesicles, and lysosomes move sequentially. A model is proposed whereby these three different classes of proteins are sorted into different vesicles in the last Golgi compartment, the trans Golgi network. This compartment corresponds to a tubular reticulum on the trans side of the Golgi stack, previously called Golgi endoplasmic reticulum lysosomes (GERL).
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