The thrombospondin-related protein CpMIC1 (CpTSP8) belongs to the repertoire of micronemal proteins of Cryptosporidium parvum

L Putignani, A Possenti, S Cherchi, E Pozio… - Molecular and …, 2008 - Elsevier
Bioinformatic data show that, in addition to TRAP-C1, Cryptosporidium parvum encodes 11
thrombospondin-related proteins (CpTSP2 through CpTSP12), none of which has been
characterized yet. We describe herein the cloning of a 2048bp-long sporozoite cDNA
encoding CpTSP8, a type I integral membrane protein of 614 amino acids, possessing three
thrombospondin type I (TSP1) repeats and one epidermal growth factor (EGF)-like domain.
Transcriptionally, CpTSP8 is represented by a fully spliced and two immature mRNA forms …