TGFβ signaling in health and disease
RJ Akhurst - Nature genetics, 2004 - nature.com
Nature genetics, 2004•nature.com
Inactivating mutations in TGFBR2, encoding the transforming growth factor-β (TGFβ) type 2
receptor, may account for up to 10% of cases of Marfan syndrome. This finding has
implications for a wider spectrum of disorders, including cancer, fibrosis and inflammatory
and cardiovascular diseases, which are influenced by TGFβ.
receptor, may account for up to 10% of cases of Marfan syndrome. This finding has
implications for a wider spectrum of disorders, including cancer, fibrosis and inflammatory
and cardiovascular diseases, which are influenced by TGFβ.
Inactivating mutations in TGFBR2, encoding the transforming growth factor-β (TGFβ) type 2 receptor, may account for up to 10% of cases of Marfan syndrome. This finding has implications for a wider spectrum of disorders, including cancer, fibrosis and inflammatory and cardiovascular diseases, which are influenced by TGFβ.
nature.com